While primitive races are confined to a single planet or system, most star-faring races are members of a multi-system or galactic government. The greatest empire are vast governments and fleets that control systems in multiple galaxies.
- The Kree Empire: The once-dominant civilisation of the Greater Magellanic Cloud.
- The Skrull Empire: The fractured empire that dominates the Andromeda Galaxy.
- The Shi’ar Empire: The dominant power of the Triangulum Galaxy and perhaps the greatest power in the Local Group.
Lesser Empires and Organisations
- The Eternals of Titan: A race of advanced super-beings who live on the moon Titan in the Sol System. Most are content to leave the universe in peace – except for the Mad Titan, Thanos.
- The Badoon Hegemony: A fading empire that at one time controlled more than 70% of the Milky Way Galaxy.
- The Rigellian Empire: The Rigellians rule dozens of star systems in the Milky Way, along with a similar number in the Andromeda Galaxy.
- The Nova Corps: An intergalactic peace-keeping force, controlled by the Worldmind of Xandar, that protects civilisations in the Milky Way and Andromeda Galaxies.
- Omega Core: A pan-galactic custodial force charged with capturing and imprisoning major criminals in the Kyln.